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Administered via the nose-to-brain drug delivery (NBDD) pathway, BA-LP demonstrates significant brain targeting and enhanced bioavailability, thereby improving drug efficacy and offering a novel therapeutic strategy for ischemic stroke (Xiang et al., 2020) has been shown to mitigate allergic rhinitis (AR) symptoms in rat models by inhibiting the release of immunoglobulin E (IgE), histamine, interleukin-1, interleukin-4 (IL-4), interleukin-6 (IL-6), and tumor necrosis factor- (TNF-) ( 2.1.2 Baicalein Baicalein and baicalin are flavonoids extracted from the rhizome of the traditional Chinese medicine Scutellaria baicalensis, with distinct differences in chemical structure and biological activity

Others rely primarily on injections with periodic infusions for deeper support

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